Presentation on Personalized Health Care: a data mining challenge in clinical decision support

On Friday, Jan 20th, Saskia van Loon will give a talk on Personalized Health Care.  Saskia performs a PhD project in the TU/e Information Systems group (supervisors: Anna Wilbik, Uzay Kaymak), in collaboration with Catharina Ziekenhuis Eindhoven (supervisors: Arjen-Kars Boer, Volkher Scharnhorst).

Where: TU/e, Paviljoen, K16

When: 12:30-13:30
Agenda Item: see http://is.ieis.tue.nl/?ai1ec_event=1457-2

Abstract: 

The focus of this PhD project (as part of Impuls 2) is on improving decision making by healthcare professionals through providing decision support based on fusing data from multiple sources, including patient self-monitoring information. The health information gathered in daily life circumstances complements information from professional diagnostic tools and can thereby contribute to clinical decision making. Philips Research has developed a prototype eWatch that is able to collect different hemodynamic parameters based on photoplethysmography. Within the PhD project, special attention will be given to laboratory data from the Catharina Hospital as many high- quality data are generated here and the data are also well documented. One part of the project is focused on cardiology, i.e. categorizing and treating heart failure as well as on improving the outcome of cardiac resynchronization therapy (CRT). Heart failure is now categorized in four stages based on subjective data. The categorization of heart failure is used in clinical decision making, where cardiac treatment eligibility is partially based on the stage of heart failure. Combining diagnostic patient data and monitoring cardiac functioning in daily life can objectify this classification of heart failure and subsequently improve outcome of different cardiac therapies. CRT is performed by implanting a device, i.e. an implantable cardioverter-defibrillator (ICD) or pacemaker, equipped with an additional lead stimulating the left ventricle. In 70% of the patients this will resynchronize the cardiac ventricular contractions and improve cardiac output. However, until now, 30% of patients does not respond for unknown reasons. Combining available patient data and monitoring of these patients in daily life circumstances provides information that can improve the success rate of this procedure. The second part of the project is focused on bariatric surgery. The number of patients with obesity and morbid obesity is increasing steadily. Sometimes a bariatric surgery such as gastric bypass or sleeve, is the only treatment option. Patients eligible for a bariatric surgery are screened by a multidisciplinary team of the obesity clinic of the Catharina Hospital. Here, decision support is needed as patient data is coming from multiple sources and success of the treatment is hard to predict beforehand. Predictive models are built based on the multiple source data, with special attention to laboratory data, modelling weight loss, improvement of comorbidities and quality of life.

Presentation: Designing for Shared Decision-Making

On Friday, May 20th, Ingeborg Griffioen will give a talk on Designing for Shared Decision-Making. 

Where: TU/e, Paviljoen, K16
When: 12:30-13:30
Agenda Item: see http://is.ieis.tue.nl/wp/?page_id=43&ai1ec_cat_ids=14

Abstract: Shared Decision-Making (SDM) is a process in which a doctor informs a patient about available treatments and options, potential benefits and risks and patient understanding is checked. The patient informs the doctor about his or her values, preferences, fears, lifestyle, believes and knowledge. Based upon this shared knowledge, pros and cons are discussed, after which the doctor expresses a preferred option with background reasoning and finally ideally consensus is achieved together.
Systematic reviews showed that higher levels of involvement of patients in decision-making resulted in better quality of care, increased satisfaction (for both patients and medical staff), improved self-esteem for patients, it helps patients address their information needs, and it can promote deliberate treatment decisions. However, implementation in daily medical practice appears limited. SDM is confronted with several barriers.
Where should designers start working to improve shared decision-making? How can they help both health seekers and health professionals to effectively participate and co-operate in SDM? From a designer perspective it makes sense to improve SDM by considering (and if necessary redesigning) all potential contributing (or negatively influencing) factors.
In this presentation an overview of factors and challenges relevant for designers will be presented.

Master Thesis defense by Maarten Kooijman on GameBus

On Monday, February 15th, 2016, Maarten Kooijman will defend his master thesis entitled “The potential of a mobile health rewarding app (GameBus) for people with  Intellectual disabilities”.  Everyone is cordially invited to join to learn, ask questions and give feedback.

Where: TU/e, Paviljoen building, room K10

When: 13:00-14:00

Stakeholders:

  • Supervisors TU/e: Dr. P.M.E. (Pieter) Van Gorp, Prof. Dr. J.H.D.M (Joyce) Westerink
  • Supervisors Lunet Zorg (the home care organization at which the practical work was performed): P. (Patrick) Leijte, R. (Ruud) Kavelaars, H.J. (Henk) van Heffen

Subject headings: HEALTH CARE; E-HEALTH; M-HEALTH, GAMIFICATION, INTELLECTUAL DISABILLITIES

Abstract: This research describes the results of a six-month graduation project within the GameBus project. GameBus is a novel app, developed within a multinationality collaboration. The app engages families and friends to stay active physically, cognitively and socially via an enjoyable personalized gaming experience. GameBus connects children, colleagues, the elderly and other family members to join physical, cognitive and social challenges, and it is unique because it crosses the boundaries of existing health apps. The app was not designed explicitly for people with intellectual disabilities. However, some issues (e.g., social isolation, insufficient physical exercise, etc.) play a role in the care for people with intellectual disabilities, as they do in care for the elderly. Therefore, it is worthwhile to investigate if health-rewarding apps like GameBus can play a role within healthcare organizations for people with intellectual disabilities. Via this master thesis project, it has been examined which clients are eligible for GameBus and how the app might be used in the future. The findings and experiences of clients and client supervisors with the application of GameBus are presented. Three promising use cases were found in which GameBus can play a role. GameBus is a valuable way to motivate and stimulate clients to perform physical, social, cognitive and other (e.g., domestic) activities.

IS-HEART presentation June 5th: Dynamic Clinical Checklist Support Systems

Also see the online agenda item for this session.

Speakers: Lonneke Vermeulen (TU/e – IS) and Ashley De Bie Dekker (Catharina Ziekenhuis Eindhoven)
Title: The first pilot study of DCCSS Tracebook, from idea to results

Abstract: Atul Gawandas’ Checklist Manifesto made the medical world realize the high potential of clinical safety checklists in reducing medical errors and improving patient safety. As the current computerized checklist support systems were too static, the Brainbridge II program (a collaboration between the Eindhoven University of Technology, Zhejiang University, Philips Research and Catharina Hospital Eindhoven) developed a system that can individualize checklists based on information from the patient’s medical record while also considering the context of the clinical workflows. By the end of last year (2014) the first pilot study of the Dynamic Clinical Checklist Support System (DCCSS) Tracebook took place in the hospital. In this presentation we will guide you from the beginning of this project to the results of the first pilot study.

After a short introduction of the Tracebook system, we will describe how we developed these dynamic checklists, which research design we followed and how the pilot study was set up. We will conclude with the promising results from the study and afterwards there is time for discussion.

Workshop on Interventional Radiology

Together with Philips, the School of Industrial Engineering is having a workshop on Interventional Radiology.  Throughout the morning of May 12th, 2015, have three presentations by Philips and three by TU/e participants from the Information Systems group as well as from the Human Performance Management group.  Also, we have a demo of the TraceBook platform, which was recently developed in collaboration with Philips research, Catharina Hospital and Zhejiang University.

IS-HEART session on Simulation in Healthcare

Speaker: Geovanny Correa Cevallos (master thesis student in Operations Management and Logistics)

Title: Computer simulation applied to interventions in healthcare: Literature Review

Abstract: When ethical principles and financial convenience enter in the game, it is necessary to have a tool to evaluate possible changes in policies and norms.  The use of computer simulation is being proved very useful in this matter in the context of healthcare. The purpose of this presentation will be to show the results of the literature review after going through some basic concepts about simulation, intervention research, what are the available methods, and which of those fit better with the purpose of applying computer simulation in evaluating healthcare systems. At the end, the methodology proposed by Sobolev et al. (2012) is presented as a reference to conduct such type of simulation. Furthermore it will be mentioned a chance for improvement in the implementation of this method given the automatic translation method suggested by Eshuis & Van Gorp (2014)

When/where: April 24th, 2015, in K16 (see agenda).

Master Thesis Defense Sven Bastianen: Towards an architecture for the support of integrated Personal Health Records

Pieter Van Gorp is proud to announce the very successful completion of the master thesis project of Sven Bastianen.  Sven has worked closely with SAP NL and for the final presentation the large number of attendees confirmed that he tackled a very relevant problem.

MTP Defense Sven Bastianen (web)
 
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IS-HEART session by Stan Lamers

The 2nd IS-HEART session of Feb. 2015 will be scheduled in week 4 instead of week 3.

Title: Physician Order Alert Assessment Support using Data Mining Techniques.

Where: K16
When: 27/02/2015, 12:30-13:30
Also see the online agenda item.

Everybody Welome!

Abstract: During the last four decades there has been a major increase in the number of automatic reporting systems for adverse drug events (ADEs)in the healthcare setting. Computerized prescription alerts can assist in avoiding ADEs but research has indicated that one important example of an ADE is the situation where a medical specialist fails to adequately assess computerized prescription alerts. These computerized prescription alerts can be shown to a physician when for example there is a problem with the dosage of a prescribed medicine or an interaction with other medicines is found. Hospital Pharmacist Drs. P.A.G. De Klaver indicates that Maxima Medical Center’s Pharmacy has to deal with 500-800 prescription alerts on an average day, which is considered to be too high and time consuming. The alert system that is currently in use at the hospital is emphasizing the breadth of coverage instead of clinical relevance or severity of the event, which leads to low clinician acceptance of drug alerts. Many alerts can cause alert fatigue; a state in which the user becomes less responsive to alerts in general.
The aim of this research project is to find data mining techniques to create models that can support processing of prescription alerts at the Maxima Medical Center in Veldhoven. This research will not focus on all ADEs but only on drug-drug interaction effects and their alerts because those alerts are considered to be the most time consuming for pharmacy personnel.

In this presentation, an overview of recent work on improving healthcare alerts systems is given and the overall research proposal is clarified.

IS-HEART session: presentation by Wintjes, T.H.M.

Also see the agenda item in our online calendar.

Presentation by Tijmen Wintjes on his bachelor end project entitled “Improving the financial understanding of microtreatments in Mohs Micrographic Surgery”.

Presentation title: Our healthcare reimbursement system and how it affects the financials of innovative care processes.

Presentation abstract: In this talk, we have a look reimbursement of care within hospital and clinics. Who are the important parties within this process? What are their responsibilities? We then consider how our knowledge helps us to understand ways of working in healthcare. As a case study we consider the Mohs Micrographic Surgery process in the MohsA clinic. We will come to argue that the current systematic has a very significant financial impact on the ‘real’ price of the surgery. In our considerations we discuss one of the most valuable information systems in the healthcare business operated by DBC-onderhoud.


IS-HEART sessions are organized every first and third Friday of the month. Sometimes, extra sessions are organized or sessions are moved for example to the fourth week of the month. Such exceptions are scheduled as separate events in the IS agenda.

IS-HEART Talk on Lean Management by Pieter Dat

On Friday, September 5th 2014, Pieter Dat will present the results of his second master thesis. Pieter has completed his first master thesis in our TU/e IS group (see previous post). Last month, he has completed his second master on Care Management, at Erasmus University Rotterdam. In his second thesis, Pieter has investigated Lean Management at the Maxima Medisch Centrum.

As usual, the IS-HEART session is organized in Paviljoen K16, from 12:30 to 13:30.

Further information:

Abstract master thesis (EUR): evidence in Lean Management (“Lean capacity planning and accessibility of healthcare services:
Development of a continuous improvement culture or application of instruments and tools”)

Research question and objective:
Lean Management is characterised by a continuous improvement culture within an organisation and has resulted in improvements of business processes in several industries. A differentiation in the theory of Lean Management can be made between an organisational and an operational perspective. Lean Management is increasingly applied in the healthcare domain. In the Máxima Medisch Centrum (MMC, Eindhoven / Veldhoven) employees working at the operational level use instruments and tools to apply Lean Management. The central scientific research question is formulated as: “How can Lean Management tools and instruments contribute to continuous process improvement in the Máxima Medisch Centrum?” This research project aimed at analysing how the use of instruments and tools leads to (the development of) continuous improvement in the organisation.

Research design and research methodologies:
The research consisted of case studies at two outpatient departments in the Máxima Medisch Centrum. Four research methodologies are applied, in a triangular approach: 1) semi-structured questionnaire, 2) data analysis of Key Performance Indicators (KPI’s), 3) document analysis and 4) semi-structured interviews.

Results and conclusion:
The master thesis project lead to insights in the current maturity of the application of Lean Management in the Máxima Medisch Centrum. Recommendations, regarding the applicability and prerequisites, are drawn for further development of a continuous improvement culture in the hospital.